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Obesity reprogrammes muscle stem cells

Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden. In a new study, doctoral student Cajsa Davegårdh has studied so-called DNA methylation in muscle stem cells in both obese and non-obese individuals. DNA methylation is an epigen

https://www.ludc.lu.se/article/obesity-reprogrammes-muscle-stem-cells - 2026-01-09

An Innovative Medicines Initiative Project for Precision Medicine in DKD

BEAt-DKD (“Biomarker Enterprise to Attack Diabetic Kidney Disease”), a unique public private partnership funded by the Innovative Medicines Initiative (IMI), member companies from the European Federation of Pharmaceutical Industries and Associations (EFPIA), the Juvenile Diabetes Research Foundation (JDRF) and the state of Switzerland has announced the launch of a 5-¬¬year project (total budget 28

https://www.ludc.lu.se/article/innovative-medicines-initiative-project-precision-medicine-dkd - 2026-01-09

100 million SEK for personalized medicine in Diabetes

Almost 0.5 billion people have diabetes globally, many of whom are unaware of their condition; within the next two decades, this number is expected to double, largely owing to a growing, ageing, and increasingly industrialized global population. Lund University receives 100 million SEK from The Swedish Foundation of Strategic Research to help stop this development. “This is excellent news and a fa

https://www.ludc.lu.se/article/100-million-sek-personalized-medicine-diabetes - 2026-01-09

Unique mapping of methylome in insulin-producing islets

Throughout our lives, our genes are affected by the way we live. Diet, exercise, age and diseases create imprints that are stored in something called methylome. Now, for the first time, researchers at the Lund University Diabetes Centre in Sweden have been able to map the entire methylome in the pancreatic islets which produce insulin, and the researchers have made several important discoveries. U

https://www.ludc.lu.se/article/unique-mapping-methylome-insulin-producing-islets - 2026-01-09

Successful research funded by the European Research Council

Six researchers from Lund University Diabetes Centre have recieved prestigous grants from the European Research Council (ERC). In order to celebrate the success we invited the public to an open seminar. Some of the talks can be reviewed here (in Swedish). Forskning för bättre folkhälsa:Framsteg inom typ 2-diabetes, fetma och hjärtsjukdomar   Professor Olle Melander: Hormoner – gårdagens livräddare

https://www.ludc.lu.se/article/successful-research-funded-european-research-council - 2026-01-09

From injections to pills - the research on neonatal diabetes

They govern everything we think and do, they give us the ability to feel pain and to secrete insulin: they are the ion channels that are present in every one of our cells and that control the electrical impulses in our nerve and muscle cells. “For me, they are the very spark of life”, says Dame Frances Ashcroft, professor at the University of Oxford, who is also now to be an honorary doctor at Lun

https://www.ludc.lu.se/article/injections-pills-research-neonatal-diabetes - 2026-01-09

200.000 euro to diabetes research

Four researchers have been awarded grants from The Bo and Kerstin Hjelt Diabetes Foundation. The grant consists of Euro 50 000 each and are aiming towards better treatments and prevention of type 2-diabetes. Improved life expectancy and quality of people with diabetesDiabetes affects millions of patients around the world. The two main types of the disease, type 1 and type 2, are both characterized

https://www.ludc.lu.se/article/200000-euro-diabetes-research - 2026-01-09

The role of vitamin A in diabetes

There has been no known link between diabetes and vitamin A -- until now. A new study suggests that the vitamin improves the insulin producing β-cell´s function.The researchers initially discovered that insulin-producing beta-cells contain a large quantity of a cell surface receptor for vitamin A. "There are no unnecessary surface receptors in human cells. They all serve a purpose but which, in ma

https://www.ludc.lu.se/article/role-vitamin-diabetes - 2026-01-09

New research describes the differences between mice and humans

Research from King’s College in London, UK, and Lund University in Sweden could explain why diabetes drugs which have worked in animal experiments are not equally successful in humans. The researchers discovered differences – but also unknown similarities – in the function of insulin-producing beta cells. The team have mapped a category of receptors, known as G protein-coupled receptors, which con

https://www.ludc.lu.se/article/new-research-describes-differences-between-mice-and-humans - 2026-01-09

LUDC-IRC ready for take off

Taking advantage of a novel sub-classification of diabetes LUDC-IRC, a newly launched collaboration between academia, the health care system and industry, aims at delivering precision medicine in diabetes.  - We have set the bar high. We very specifically aim at making a difference for diabetes patients by the end of this eight year program. We need to find smart ways to use all resources we colle

https://www.ludc.lu.se/article/ludc-irc-ready-take - 2026-01-09

Newborn babies to be screened for studies on type 1 diabetes and celiac disease (gluten intolerance)

Can insulin taken as an infant in small doses together with food render the immune system used to insulin and thus prevent type 1 diabetes? Can a gluten-free diet and probiotics prevent celiac disease (so called gluten intolerance)? These questions will be asked by two separate studies that are being planned at Lund University in Sweden. A new comprehensive screening of newborn babies in southern

https://www.ludc.lu.se/article/newborn-babies-be-screened-studies-type-1-diabetes-and-celiac-disease-gluten-intolerance - 2026-01-09

New drink keeps blood sugar in check

Food researchers at Lund University in Sweden have discovered that consuming small amounts of chromium mixed with certain amino acids before eating is healthy. Why? Well, this mixture diluted in water suppresses the blood sugar spike that occurs when we eat. Now, they are hoping that the drink – which tastes like ordinary mineral water – will be able to compete with soft drinks and flavoured water

https://www.ludc.lu.se/article/new-drink-keeps-blood-sugar-check - 2026-01-09

The risk of type 1 diabetes not increased by swine flu vaccine Pandemrix

There has been a fear that the swine flu vaccine, Pandemrix, would increase the risk of autoimmune diseases other than narcolepsy. However, a new study of children from Sweden and Finland shows that the vaccine increased neither the risk of developing autoantibodies against insulin-producing beta cells nor the occurrence of type 1 diabetes. “On the contrary, the risk was reduced among vaccinated c

https://www.ludc.lu.se/article/risk-type-1-diabetes-not-increased-swine-flu-vaccine-pandemrix - 2026-01-09

Can synthetic controls improve causal inference in interrupted time series evaluations of public health interventions?

Advances in synthetic control methods bring new opportunities to conduct rigorous research in evaluating public health interventions. However, incorporating synthetic controls in interrupted time series studies may not always nullify important threats to validity nor improve causal inference. Read the paper at https://academic.oup.com/ije/article/49/6/2010/5917161

https://www.lupop.lu.se/article/can-synthetic-controls-improve-causal-inference-interrupted-time-series-evaluations-public-health - 2026-01-09

Reflection on modern methods: Statistics education beyond ‘significance’: novel plain English interpretations to deepen understanding of statistics and to steer away from misinterpretations

Concerns have been expressed over standards of statistical interpretation. Results with P <0.05 are often referred to as ‘significant’ which, in plain English, implies important. This leads some people directly into the misconception that this provides proof that associations are clinically relevant. Read the paper at https://academic.oup.com/ije/article/49/6/2083/5876177

https://www.lupop.lu.se/article/reflection-modern-methods-statistics-education-beyond-significance-novel-plain-english - 2026-01-09

Reflection on modern methods: demystifying robust standard errors for epidemiologists

Standard errors are usually calculated based on assumptions underpinning the statistical model used in the estimation. However, there are situations in which some assumptions of the statistical model including the variance or covariance of the outcome across observations are violated, which leads to biased standard errors. Read the paper at https://academic.oup.com/ije/article/50/1/346/6044447

https://www.lupop.lu.se/article/reflection-modern-methods-demystifying-robust-standard-errors-epidemiologists - 2026-01-09